Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Quantitation of human thymus/leukemia-associated antigen by radioimmunoassay in different forms of leukemia

Abstract

Using a radioimmunoassay, increased levels of a human thymus/leukemia-associated antigen (HThy-L) have been detected in leukemic cells and plasma from most patients with E-rosette-positive acute lymphoblastic leukemia (ALL) and a number of patients with E-rosette-negative ALL, acute myeloblastic leukemia (AML), acute monomyelocytic leukemia (AMML), and acute undifferentiated leukemia (AVL).… Read more

Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Diagnostic considerations in ataxia-telangiectasia

Abstract

13 children with ataxia-telangiectasia were followed for 6 years. Unlike previously reported cases, these patients had progressive, debilitating neurological disease and slight pulmonary or infectious symptoms. Immunological dysfunction was variable and endocrinological defects were absent. Oculomotor findings, alpha-fetoprotein levels, and the incidence of chromosomal breakage were the most consistent parameters in the diagnosis of the condition.… Read more