Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Immune status of blood product recipients

Abstract

Persons with hemophilia are at risk of the acquired immunodeficiency syndrome (AIDS), and clinically asymptomatic hemophiliacs have shown a high incidence of AIDS-like immune abnormalities, facts leading to speculation that many hemophiliacs have been exposed to the AIDS agent through their blood products.… Read more

Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Klebsiella pneumoniae: selected virulence factors that contribute to pathogenicity

Abstract

Klebsiella pneumoniae infections occur in humans of all ages, however the highest risk groups appear to be infants, the elderly and the immunocompromised. One or more virulence factors may contribute to pathogenicity in humans. In this article we review three factors that may mediate virulence: cell wall receptors, capsular polysaccharide, and endotoxin.… Read more

Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

The epidemiology of nosocomial infections caused by Klebsiella pneumoniae

Abstract

Klebsiella pneumoniae causes serious epidemic and endemic nosocomial infections. We conducted a literature review to characterize the epidemiology of epidemic K. pneumoniae outbreaks. Eighty percent of the outbreaks (20/25) involved infections of the bloodstream or urinary tract. Person-to-person spread was the most common mode of transmission, and nearly 50% of the outbreaks occurred in neonatal intensive care units.… Read more