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Nosocomial transmission of multidrug-resistant Mycobacterium tuberculosis. A risk to patients and health care workers


OBJECTIVE: To determine the factors associated with the development of multidrug-resistant tuberculosis among patients at a New York City Hospital and to investigate possible nosocomial transmission.

DESIGN: A retrospective case-control study and tuberculin skin test survey.

PATIENTS: Twenty-three patients with tuberculosis whose isolates were resistant to at least isoniazid and rifampin (case patients) were compared with patients with tuberculosis whose isolates were susceptible to all agents tested (controls).… Read more