Month: December 2002

Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Peripheral blood cell-specific cytokines in persons with untreated HIV infection in Malawi, Africa

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Abstract

Human immunodeficiency virus (HIV) infection is the primary cause of morbidity and mortality in Malawi, Africa, because of its many effects on the immune system. Immune cells communicate through cytokines; therefore, we examined the relationships between HIV serostatus and cell-specific cytokine production for 40 asymptomatic, employed adults and 312 acutely ill, hospitalized patients in Malawi.… Read more

Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Demographic and immune correlates of human herpesvirus 8 seropositivity in Malawi, Africa

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Abstract

BACKGROUND: In the USA, human herpesvirus 8 (HHV-8) is associated with Kaposi’s sarcoma (KS) and HIV infection. We examined HHV-8 seroprevalence in a Malawian cohort, and assessed its relationship with HIV, KS, demographic characteristics, and immune findings.

METHODS: In 1997 and 1998, blood samples were obtained from 272 hospitalized Malawian patients, for whom demographic information was obtained, and 24 healthy volunteers without demographic data.… Read more