Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Echovirus type 7 meningitis in young children


Clinical and virological features are presented of an epidemic of aseptic meningitis in children caused by echovirus type 7. The majority of patients were younger than 1 year of age. Symptoms varied according to age. The degree of CSF pleocytosis was inversely related to age and was significantly greater in infants 7 months of age and younger than in those older than 7 months. A CSF polymorphonuclear pleocytosis was documented in 66% of the cases. Human placental fibroblast provided a more rapid detection of cytopathic effect and improved final recovery rates when compared with rhesus monkey kidney cells, Vero cells, and human epidermoid (Hep-2) cells. Several possible explanations for the sudden appearance of echovirus type 7 activity are discussed.

Jarvis WR, Tucker G

Am. J. Dis. Child. 1981 Nov;135(11):1009-12

PMID: 7294004