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Patient cytokine response in transfusion-associated sepsis

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Abstract

Cytokine concentrations in plasma from patients transfused with packed erythrocytes contaminated with gram-negative bacilli were measured. Cytokine concentrations in posttransfusion plasma were significantly elevated. A difference in cytokine patterns between survivors and a nonsurvivor was observed.

McAllister SK, Bland LA, Arduino MJ, Aguero SM, Wenger PN, Jarvis WR

Infect. Immun. 1994 May;62(5):2126-8

PMID: 8168982