Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

HTLV-III/LAV-seronegative, virus-negative sexual partners and household contacts of hemophiliacs


Public concern about the transmissibility of human T-cell lymphotropic virus type III/ lymphadenopathy-associated virus (HTLV-III/LAV) has been heightened by several
reports suggesting the existence of an antibody-negative, virus-positive state in some asymptomatic sex
partners of persons who are antibody-positive.  We recently evaluated 88 household members and/or sex partners of persons with hemophilia and found that only two nonhemophiliacs were HTLV-III/LAV antibody-positive.  We report herein the results of culturing peripheral blood lymphocytes of 20 of the nonhemophiliac contacts whose index hemophiliac was antibody-positive.

McFadden T, Jason JM, Feorino P

JAMA 1986 Apr;255(13):1702 (Letter to the Editors)

PMID: 3005673