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Janine Jason, M.D.

Janine Jason, M.D. Pediatrics, Board-certified Immunology/Allergy, Board-eligible
404-483-1830
Clinical and Research Expertise in Infectious Diseases Trained in the Epidemiology Intelligence Service (EIS) Program, Centers for Disease Control & Prevention Dr. Jason has over 35 years of research experience, clinical expertise and numerous peer-reviewed publications.
Education
M.D. Medicine1975Harvard Medical Schoolharvard
B.A. Biology1971University of ChicagoUniversity_of_Chicago_Modern_Etched_Seal_1.svg
Summary of Expertise
Accidental needlestick injuriesDr. Jason has analyzed the incidence and healthcare costs associated with community- and occupationally-acquired accidental needlestick injuries in the United States.
Acquired immunodeficiency syndrome (AIDS)Dr. Jason has done extensive research concerning the clinical, epidemiologic, and immunologic aspects of HIV and AIDS, including HIV transmission, related opportunistic infections, and associated morbidity and mortality.
Bacillus Calmette-Guerin vaccine, Mycobacterium tuberculosis, tuberculosisDr. Jason designed, supervised, analyzed, and published a study assessing the immunology of Bacillus Calmette-Guerin (BCG) vaccine and its ability to prevent mycobacterial infections.
BioethicsIn her various positions at the Centers for Disease Control and Prevention, Dr. Janine Jason has dealt with the ethical issues surrounding policy decisions involved in hemophilia-AIDS, transfusion-associated AIDS, AIDS in developing countries, AIDS prevention, child abuse, and child homicide prevention. She has served as a member of the CDC IRB Committee and on safety monitoring committees for NIH clinical trials.
BiomedicineDr. Jason has done extensive research concerning a wide variety of biomedical topics, including prognostic markers, pathogenesis, immune correlates and therapy of HIV, AIDS, Kawasaki Disease, various bacterial, viral, and parasitic infections, and sepsis/bloodstream infections. These are reflected in her numerous publications on these topics.
Cellular immunity/Cellular immunologyDr. Jason has done extensive research concerning the T-cell antigen receptor, superantigens, cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection.
Clinical Flow CytometryDr. Jason has numerous publications in which she has used four-color, six-parameter flow cytometry to examine cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection. She is a world's expert in using a flow cytometric approach to examining these issues, as evidenced by her numerous publications in peer-reviewed journals.
Clinical ImmunologyDr. Jason has published extensively on primary and secondary immunodeficiency. She trained with Dr. Erwin Gelfand and Drs. Janeway Senior and Junior. Dr. Jason has been on the Emory University faculty, caring for patients, training Fellows, and doing research concerning clinical immunologic issues for the past 23 years.
Clinical MedicineDr. Jason graduated from Harvard Medical School, did her residency at the Children's Hospital of Los Angeles, and completed an immunology fellowship at Hospital for Sick Children, Toronto. She was on faculty at Yale University of Medicine prior to moving to Atlanta, where she has been on the clinical faculty of Emory University School of Medicine for 23 years, attending in and teaching pediatrics, immunology, and infectious diseases. Dr. Jason has provided advice, consultation, and lectures to numerous universities, hospitals, organizations, and ministries of health.
Clinical ProtocolsDr. Jason was responsible for the design, execution, and analysis of the epidemiologic and immunologic components of several multicenter studies concerning hemophilia-associated AIDS. She was responsible for the design of these protocols, as well as for their submission to and clearance through numerous Institutional Review Boards and advisory groups. These studies were done in collaboration with the National Institute of Health, a large number of universities, and medical treatment facilities. Their nature and productivity are reflected in numerous publications in peer-reviewed journals.
Clinical Research, Clinical Research Management, Clinical StudyDr. Jason has designed and managed numerous clinical research studies, most notably in the area of hemophilia-associated AIDS. She has been responsible for protocol design, study coordination, data analysis, and preparation of manuscripts submitted and accepted by peer-reviewed journals. These skills are reflected in her numerous publications. For the above-mentioned studies, Dr. Jason was the primary contact person for coordination with universities, health institutions, and federal agencies. She was responsible for clearance of protocols through Institutional Review Boards and for updating these Boards and Institutions about study activities. Dr. Jason supervised data collection, management, and analysis. She dealt with problems at the patient, practitioner, and institutional levels. Her skill at successfully managing clinical research studies are reflected in her numerous publications.
Cronobacter sakazakiiDr. Jason has reviewed legal cases involving the clinical and epidemiologic aspects of Cronobacter sakazakii (formerly Enterobacter sakazakii) infections in infants.
CytokinesDr. Jason is a world expert in evaluation of cell-specific cytokines in humans. She has evaluated and published primary research on the cytokine network in healthy individuals at various ages and also in a wide variety of disease states, including sepsis, bloodstream infections, HIV infection, malaria, and malnutrition.
Infectious and immunologic disordersDr. Jason has published primary research concerning a number of diseases, including but not limited to HIV infection, HTLV, Kawasaki disease, bloodstream infections, malaria, parvovirus infection, Salmonella and other enteric infections, malaria, tuberculosis and nontubercular mycobacteria, Kaposi sarcoma, malnutrition, and vitamin A deficiency.
Cronobacter infectionsincluding those formerly known as Enterobacter sakazakiiDr. Jason has reviewed legal cases involving the clinical and epidemiologic aspects of Cronobacter sakazakii infections in infants.
EpidemiologyDr. Jason trained in epidemiology and public health at the Centers for Disease Control and Prevention, in (CDC)'s Epidemiology Intelligence Service (EIS) and Preventive Medicine Residency Program. She was an adjunct associate professor at the Rollins School of Public Health at Emory University for nine years and, as a respected medical epidemiologist, chaired and/or was a member of numerous committees, including CDC's EIS Course Survey Committee, CDC's EIS Conference Planning Committee, CDC's Medical the Advisory Board, CDC's Institutional Review Board, the Public Health Service (PHS)'s Promotion Board, National Institute of Health (NIH)'s Data and Safety Monitoring Board for the Clinical Trial of Intravenous Gammaglobulin in HIV-Infected Children, and the National Collaborative Hemophilia Growth & Development Study Executive Committee. Dr. Jason held a number of positions at CDC, including as a Medical Epidemiologist in the Office of the Director, Center for Health Promotion and Education; Chief of the Epidemiology Studies Section in the Division of Host Factors, Center for Infectious Diseases (CID); Chief of Applied Communications Research, Epidemiology & Evaluation, National AIDS Information and Education Program; and Chief of the Immunoregulatory Laboratory, NCID. Dr. Jason has supervised outbreaks involving infectious diseases, blood product contamination, and violence. She designed, supervised, analyzed, and reviewed numerous epidemiologic and clinical outbreaks and studies and supervised CDC's Hemophilia-Associated AIDS Surveillance System. Dr. Jason has a unique combination of epidemiologic, clinical, and basic laboratory training and experience. She has been involved in numerous peer-reviewed publications, Morbidity and Mortality Weekly Reports, and PHS recommendations on areas ranging from child health, HIV, blood product safety, infectious diseases, immunodeficiency, to violence.
Health managementDr. Jason spent 23 years at the Centers for Disease Control and Prevention, performing research and assisting in policy making concerning health management issues, especially in the areas of child health, infectious disease prevention, and sexually transmitted diseases. In addition, she has published a parenting book for the layperson concerning management of the health of premature infants. This parenting book was published in hardback by Henry Holt, Inc., and in paperback by Doubleday Dell, Inc. She is currently working on two books for the layperson concerning adolescent health.
ImmunizationDr. Jason is a board certified pediatrician with subsequent training in immunology. She has done studies and published concerning the immunology and efficacy of BCG vaccine, as well clinical and bench research related to a number of vaccine-preventable diseases.
Host resistanceDr. Jason has numerous publications in which she has used four-color, six-parameter flow cytometry to examine cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection. She is a world's expert in using a flow cytometric approach to examining these issues, as evidenced by her numerous publications in peer-reviewed journals. She has also examined the roles of nutrition, vitamin A, and BCG vaccination on host resistance to infection.
Human immunodeficiency virus (HIV) & AIDSDr. Jason has done extensive research concerning the clinical, epidemiologic, and immunologic aspects of HIV and AIDS, including HIV transmission, related opportunistic infections, and associated morbidity and mortality.
Humoral immunologyDr. Jason has published several papers that examine the relationships between cellular and humoral immunity in a variety of disease states, including HIV, HSV, and Kaposi sarcoma.
ImmunobiologyDr. Jason trained with Dr. Erwin Gelfand and Drs. Charles Janeway Senior and Junior, did immunobiologic research at Yale University, and did research on immunobiologic issues at the Centers for Disease Control and Prevention for the past 23 years. Her research and publications concern the T-cell antigen receptor, superantigens, cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection.
ImmunologyDr. Jason graduated from Harvard Medical School, did her residency at the Children's Hospital of Los Angeles, and completed an Immunology fellowship at Hospital for Sick Children, Toronto. She trained with Dr. Erwin Gelfand and Drs. Janeway Senior and Junior. She was on faculty at Yale University of Medicine, doing basic immunologic research, prior to moving to Atlanta, where she has been on the clinical faculty of Emory University School of Medicine for 23 years, attending in and teaching pediatrics, immunology, and infectious diseases. Dr. Jason has numerous research publications concerning the T-cell antigen receptor, superantigens, cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection.
ImmunosuppressionDr. Jason has clinical expertise managing and extensive research experience/publications concerning immunosuppression related to retroviral and other infections, malnutrition, and chemotherapy. Dr. Jason has been on the Emory University faculty, caring for patients, training Fellows, and doing research concerning clinical immunologic issues for the past 23 years.
Infectious diseasesDr. Jason is board certified in pediatrics and has training in pediatric immunology, epidemiology, and public health. She has attended in pediatric infectious diseases at Emory University for over 20 years. In addition, she frequently gives lectures, teaches courses, or mentors medical students, public health students or pediatric infectious disease fellows. She has written many peer review publications, book chapters, and surveillance reports on clinical medicine, particularly involving infectious diseases. Dr. Jason often lectures on clinical infectious diseases at national and international meetings, especially HIV and opportunistic infections associated with HIV.
InterferonsDr. Jason has done research on and has a number of papers in peer-reviewed journals concerning the role of interferon-gamma in HIV infection and bloodstream infections. She has also published concerning the relationships between cell-specific interferon-gamma production and the clinical course/outcome of various infections, as well as vitamin deficiencies and malnutrition.
InterleukinsDr. Jason has numerous publications in which she has used four-color, six-parameter flow cytometry to examine cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection. In particular, she has examined the relationships between cellular and serum IL-2, 4, 5, 6, 8, and 10, as well as the role of these cytokines in a variety of pathologic states. She is a world's expert in using a flow cytometric approach to examining these issues, and comparing various approaches to measuring interleukins, as evidenced by her numerous publications in peer-reviewed journals.
Kawasaki disease, Kawasaki syndromeDr. Jason has published on immunologic findings in Kawasaki disease, as well as provided medical care to children with this disorder.
S. aureus, including Methicillin-resistant strains (MRSA) Dr. Jason has dealt with these infections and the control of these infections in both in-patient and out-patient clinical settings.
molecular immunology involving the human immunodeficiency virusDr. Jason has done extensive research concerning the T-cell antigen receptor, superantigens, and the cytokine network, both in relation to and independent of HIV infection. She has examined the roles of various HIV molecules in HIV disease pathogenesis of HIV.
Needlestick injuries Dr. Jason has analyzed the incidence and healthcare costs associated with community- and occupationally-acquired accidental needlestick injuries in the United States.
PediatricsDr. Jason graduated from Harvard Medical School, did her residency at the Children's Hospital of Los Angeles, and completed an Immunology fellowship at Hospital for Sick Children, Toronto. She was on faculty at Yale University of Medicine prior to moving to Atlanta, where she has been on the clinical faculty of Emory University School of Medicine for 23 years, attending in and teaching pediatrics, immunology, and infectious diseases. Dr. Jason has done research concerning and published in the areas of: child health, breastfeeding, prematurity, infant mortality, child abuse, pediatric and hemophilia-related HIV infection/AIDS, Kawasaki disease, pediatrician/patient/parent communication, and parenting. Dr. Jason has provided advice, consultation, and lectures to numerous universities, hospitals, organizations, and ministries of health concerning pediatric issues.
Polycystic ovary syndrome (PCOS)Dr. Jason examined the rates, characteristics, and healthcare costs of PCOS in the United States.
Public healthDr. Jason spent 23 years in the U.S. Public Health Service (PHS), rising to the rank of Captain (retired). She was at CDC for these 23 years and is viewed as a world's expert in public health. She has interacted and collaborated with other PHS agencies, including the FDA and NIH, with the WHO, and with U.S. state health department personnel. She has collaborated with other PHS agencies on guideline development and epidemiologic studies. She has a very solid understanding of how the public health system works in the United States and throughout the world.
S. aureus, including Methicillin-resistant strains (MRSA) Dr. Jason has dealt with these infections and the control of these infections in both in-patient and out-patient clinical settings.
VaccinationAs a pediatric infectious disease expert, Dr. Jason is very familiar with vaccination strategies. She has conducted studies that assessed the impact of vaccination on infectious diseases in international settings.
Other areas of Expertise

Secondary Expertise

animal molecular biology, antibody, antibody production, antigen-antibody interaction, applied molecular biology, autoimmune disease, biological response modifier, blood sampling, cell biology, clinical laboratory, clinical laboratory equipment, clinical measurement, clinical trial design, consumer survey, cytotoxic T lymphocyte, delayed-type hypersensitivity reaction, diagnostics, health care industry quality management, health care marketing, health care system, human immunodeficiency virus testing, immunochemical assay, immunogenetics, immunoglobulin, immunoparasitology, immunosuppressive drug, medical diagnostics, molecular biology, outcomes research, preclinical research, preventive medicine, serology, strategic market planning

Basic Expertise

agglutination, allergen sensitization, biological cell, biomedical research and development, clinical diagnostics, clinical laboratory regulation, clinical virology, comparative immunology, consumer demographics, Department of Health and Social Security standard, healthcare claims substantiation research, immunochemistry, immunocytochemistry, immunodiagnostics, internal medicine, lupus erythematosus, medical expert system, medical informatics, medical lexicon, molecular immunogenetics, molecular medicine, neonatology, neuroimmunology, polymerase chain reaction, protein engineering, protein sequencing, protein synthesis, radioimmunoassay, skin test, therapy, virology

Work History
CEO2003 to PresentJason & Jarvis AssociatesDr. Jason is CEO of a medical consulting firm.
Director, Immunoregulatory Laboratory - HIV Immunology Branch, Div. of AIDS, STD, & Tuberculosis Laboratory Research1992 to 2003 Centers for Disease Control and Prevention (CDC)She conducted research and supervised research by others.
Clinical Associate Professor and Attending Faculty - Immunology, Infectious Diseases, & Epidemiology1982 to 2004Emory University School of Medicine Dr. Jason teaches, does medical consulting, and provides patient care.
Chief, AIDS Communications Research - OD (HIV) 1989 to 1992 CDCShe was in charge of the group that did research concerning AIDS communications and evaluated the effectiveness of the National AIDS Media Campaign.
Chief, Hemophilia AIDS Research & Surveillance - Division of Host Factors1983 to 1989 CDCDr. Jason was responsible for supervising all CDC's hemophilia-associated AIDS epidemiologic activities.
Medical Officer - Office of the Director, Center for Health Communications 1982 to 1983 CDCShe did research that helped found CDC's Center for Injury Control and Prevention. Her research was ground-breaking in the areas of child abuse and homicide.
EIS Officer - Epidemiology Intelligence Service (EIS) 1980 to 1982 CDCDr. Jason initiated her work at CDC through joining the world-renowned EIS Program, a training program in epidemiology, public health, and preventive medicine.
Research Associate - Immunology/Immunopathology 1978 to 1980 Yale University School of Medicine/Howard Hughes Medical Institute She performed bench research on T-cell immunology and immunoregulation.
Career Accomplishments

Associations/Societies
Dr. Jason is a world-renowned expert in the areas of immunology, HIV/AIDS, child health, and health communications. She is or has been a member of the: Society for Pediatric Research; American Association of Immunologists; American Federation for Clinical Research; American Society for Microbiology; Pediatric Infectious Disease Society; Sigma Xi, The Scientific Research Society; Clinical Immunology Society; and Phi Beta Kappa.

Licenses, certifications, and current clinical activities
She holds a medical license (M.D.) and is board-certified in pediatrics (F.A.A.P.). Dr. Jason has full medical licensure in the State of California and volunteer medical licensure in South Carolina and Oregon. She provides clinical care gratis at the Volunteers in Medicine Clinic on Hilton Head Island, SC and is actively working with her Port Orford, Oregon community to create a Port Orford/Langlois School-Based Health Center.

Professional Appointments
Dr. Jason was a Research Associate at the Yale University School of Medicine and is an Associate Professor at the Emory University School of Medicine.

Awards/Recognition
She is a Fellow of the Infectious Disease Society of America, and is a Scientific Fellow, American College of Allergy and Immunology. Dr. Jason's other honors include: Trustee Scholar, 1967-1971; L. G. Selz Scholarship, 1967-1971; Phi Beta Kappa Honor Society, 1971; Graduated with highest honors, 1971; Department of Health and Human Services Public Health Service Group Award to the "Infant Feeding Task Force," June, 1984; Public Health Service (PHS) Commendation Medal, November, 1987; PHS Outstanding Unit Citation, April, 1988; PHS Commendation Medals (three); American Society of Microbiology Lectureship, 1994-1996.

Medical/Professional Residencies and Fellowships
She did her pediatric internship and residency at the Los Angeles Children's Hospital. She had an immunology and allergy fellowship at the Hospital for Sick Children, Toronto, Ontario, Canada. She had an epidemiology fellowship with the Epidemiology Intelligence Service, CDC.

Publications and Patents
Dr. Jason has over 100 scientific, peer-reviewed publications to her credit and has authored a parenting book for the layperson. This book was published by Henry Holt (hardback) and Doubleday Dell (paperback).

Government Experience
CDC1980 to 2003Various roles (see above)
CDC1987Chairman, Epidemiology Intelligence Service Conference Planning Committee
Consulting Services

Dr. Jason is a member of the Immunology Devices Panel of the Medical Devices Advisory Committee at the U.S. Food and Drug Administration.

Dr. Jason consulted with the Armenian government concerning their newborn care network at the request of Harvard University.

She has reviewed clinical charts to advise lawyers involved in litigation, including cases involving HIV, the transmission of infectious organisms in health care settings,
Cronobacter sakazakii (formerly Enterobacter sakazakii) infection in infants, and methicillin-sensitive or methicillin-resistant Stapholococcal aureus infections (MSSA and MRSA).

Dr. Jason has lectured at numerous universities in a variety of countries concerning her areas of expertise.

She has been a member of the Public Health Service promotion board.

Dr. Jason has been a member of CDC's Institutional Review Board.

International Experience
Armenia1990Dr. Jason advised the Armenian government on organizing its neonatal transport and medical facilities and activities.
Thailand1997 to 1999Dr. Jason collaborated in studies done with the Ministry of Health concerning the immunology and pathogenesis of HIV/AIDS.
Malawi, Africa1997 to 2003Dr. Jason collaborated in studies done with the Ministry of Health concerning the immunology and pathogenesis of HIV/AIDS.
Mozambique, Africa2000 to 2003Dr. Jason collaborated in studies done with the Ministry of Health concerning the immunology and pathogenesis of HIV/AIDS.
Additional Experience
Expert WitnessDr. Jason has reviewed select cases as an expert consultant.
Training/SeminarsShe has given numerous lectures and participated in college and graduate level teaching in her areas of expertise.
Other Relevant ExperienceDr. Jason has designed and analyzed numerous medical studies and also advised in these areas.
Hobbies and Interests

Dr. Jason is an avid reader, as well as being an author of non-science-related fiction and nonfiction materials for the layperson. She enjoys traveling, nonparticipant observation, political analysis, counseling and befriending, photography, animal care, gardening, and manual labor. She leads a bicoastal life, spending Autumn through Spring on Hilton Head Island, South Carolina and Summers in Port Orford, Oregon and San Francisco, California.